Balancing Carbohydrates in Your Diet During GLP-1-Assisted Weight Loss for Women

By 
Dr Amit Kumar Singh
 on 
Nov 13, 2024
 • 
5
 min read

Struggling with weight loss, despite your best efforts, can be incredibly frustrating. Have you ever felt like you're doing everything right but not seeing the results you deserve? You're not alone—many women face the same battle, trying diet after diet without lasting success. In fact, nearly 67% of adult women in England were classified as overweight or obese in 2021, illustrating widespread struggles with weight management. Additionally, studies on eating behaviours show that 19% of women report significant issues with food, including feelings of being out of control with eating, which can contribute to the sensation of being stuck in a weight loss journey.

Enter GLP-1 agonists, medications that offer new hope for women struggling with weight loss.  These medications help regulate appetite, increase feelings of fullness, and reduce overall food intake. While these medications support weight loss, proper nutrition remains essential to maximise the benefits. One of the most misunderstood areas? Carbohydrates. Are you worried about balancing carbs while on GLP-1 therapy? Let’s explore how to get it right without sacrificing the foods you love.

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Role of GLP-1 Agonists in Weight Loss

GLP-1 (glucagon-like peptide-1) agonists are known for their role in supporting weight loss. Here is how they help you in the weight management journey: 

  • Appetite suppression: GLP-1 agonists reduce hunger by acting on the brain's appetite centres, making it easier to control food intake.
  • Delayed gastric emptying: GLP-1 slows down the emptying of the stomach, which leads to prolonged feelings of fullness after meals, helping to reduce overall calorie consumption.
  • Improved insulin sensitivity: GLP-1 enhances insulin secretion in response to meals, improving blood sugar control and reducing fat storage.
  • Reduction in food cravings: Studies show that GLP-1 helps decrease cravings, particularly for high-fat and high-sugar foods, further supporting weight loss efforts.
  • Promotion of fat loss: GLP-1 therapy specifically targets fat loss rather than muscle mass, which helps improve body composition during weight loss.

Clinical studies supporting the role of GLP-1 in weight loss

  • GLP-1 agonist and weight loss
    In a STEP 1 clinical trial, semaglutide, a GLP-1 RA, demonstrated an average weight loss of 15% to 17% over 68 weeks when combined with lifestyle changes. This was significantly greater than the placebo group, which showed minimal weight loss. 

The STEP 2 clinical trial  reported that GLP-1 leads to clinically meaningful reductions in body weight among overweight and obese individuals.

  • Comparative effectiveness
    A systematic review and network meta-analysis comparing various GLP-1 RAs found that all analysed drugs effectively reduced body weight while also controlling blood glucose levels when compared to placebo.
  • Long-term weight maintenance 

In a STEP 4 clinical trial, participants who switched to placebo after 20 weeks of semaglutide treatment experienced a 6.9% regain of body weight. The participants were not subjected to any lifestyle adjustments. This highlights that the GLP-1 therapy should go hand in hand with dietary adjustments and exercise.  

Understanding Carbohydrates

Carbohydrates are the body’s primary source of energy, but not all carbs are created equal. Here is what you should know about carbohydrates to understand its impact on weight loss: 

Simple carbohydrates vs complex carbohydrates: 

Simple carbohydrates consist of sugars that are quickly absorbed by the body, leading to rapid increases in blood sugar levels. Common sources include:

  • Table sugar
  • Honey
  • Fruit juices
  • Soft drinks

While complex carbohydrates are made up of longer chains of sugar molecules, which take longer to digest. They provide a more gradual release of energy and include:

  • Whole grains (e.g., brown rice, whole wheat bread)
  • Legumes (e.g., beans, lentils)
  • Vegetables

A prospective cohort study found that increased intake of whole grains and non-starchy vegetables was associated with weight loss. While participants who consumed refined grains showed more weight gain.

Glycemic index and its impact on blood sugar

The glycemic index (GI) measures how quickly foods raise blood glucose levels. Foods with a high GI can lead to rapid spikes in blood sugar, followed by crashes that may increase hunger and lead to overeating. Conversely, low-GI foods result in more stable blood sugar levels.

The UK’s Scientific Advisory Committee on Nutrition (SACN) emphasises the importance of considering both the quantity and quality of carbohydrates in the diet. They recommend limiting free sugars to less than 5% of total energy intake to mitigate risks associated with high GI foods, such as obesity and type 2 diabetes.

Studies supporting the role of carbohydrates in weight management

Source of carbohydrate

A study published in 2023, evaluated weight changes in 136,432 adults. 83.5% of the participants were women, average age 50. The study reported that the quality of carbohydrates they ate appeared to play a role in weight control. A daily increase of 3.5 ounces of low-quality carbohydrates, such as sugar-sweetened drinks, refined grains, and starchy vegetables was associated with gaining up to three pounds over a four-year period. While an increase of just one-third ounce of fibre in participants' daily diets cut the weight gain by half. The associations were especially strong in women. The study concluded that refined carbohydrates such as white pasta, white bread, white rice, and chips appeared more problematic, contributing even more to middle-age weight gain..

Dietary recommendations

The SACN recommends that carbohydrates should make up approximately 50% of total dietary energy intake for adults. It emphasises the importance of dietary fibre. High-fibre foods not only promote satiety but also support digestive health.

Balancing Carbohydrates for GLP-1 Success

Carbohydrate needs vary based on several factors, and tailoring intake to individual circumstances ensures better results.

  • Personalised approach: Age, activity level, and individual weight loss goals play a role in determining how much carbohydrates one should consume. Women who are physically active may require higher carbohydrate intake, while those with sedentary lifestyles may benefit from reduced carb consumption.
  • Recommended daily carbohydrate intake for women on GLP-1 therapy: The British Nutrition Foundation recommends that women should consume at least 267g (or 50% food energy) of carbohydrates daily. Though this can be adjusted based on individual factors.
  • Quality over quantity: Rather than focusing solely on carbohydrate quantity, it's crucial to prioritise quality. Whole, unprocessed carbs, such as quinoa, brown rice, and sweet potatoes, which provide sustained energy and essential nutrients, supporting overall health and weight loss efforts.
  • Nutritional deficiency due to excessive carbohydrate restriction: While reducing carbs can be beneficial for weight loss, cutting them too drastically can lead to fatigue, nutrient deficiencies, and a slowdown in metabolism. It’s important to strike the right balance.
  • Meal planning: Distributing carbohydrates throughout the day helps maintain steady energy levels. Focus on consuming complex carbohydrates earlier in the day, when energy demands are higher, and keep evening meals lighter.
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Additional Tips for Success

In addition to managing carbohydrates, other factors play a role in achieving success during GLP-1-assisted weight loss.

  • Exercise: Regular physical activity is a critical component of weight loss as it helps burn calories, build muscle, and boost metabolism. Studies show that combining exercise with a calorie-controlled diet enhances fat loss, while preserving lean muscle mass. For optimal results, a mix of cardiovascular exercise and strength training is recommended.
  • Hydration: Staying properly hydrated aids weight loss by supporting metabolism, improving digestion, and helping the body use fat as energy. Drinking water before meals can reduce hunger, leading to lower calorie intake. Research suggests that drinking 500ml of water before meals can boost weight loss by increasing satiety.
  • Mindful eating: Practising mindful eating, paying attention to hunger and fullness cues, can help women avoid overeating and make more thoughtful food choices, supporting both weight loss and emotional well-being.
  • Consulting a healthcare professional: Every individual’s carbohydrate needs differ, especially when using GLP-1 agonists. Consulting with a healthcare provider or dietitian can ensure that carbohydrate intake is optimised for both weight loss and overall health.

Conclusion

Balancing carbohydrates during GLP-1-assisted weight loss doesn’t have to be overwhelming. By understanding the types of carbohydrates, focusing on whole and fibre-rich options, and tailoring intake to your needs, you can support both your weight loss and overall health. Remember, it’s not about cutting out carbs entirely but choosing the right ones in the right amounts.

Have any questions or personal tips to share about balancing carbs? Drop a comment below, or share this article with others who might benefit! If you are looking for personalised guidance, don’t hesitate to book a consultation with us at SheMed. We can help tailor a plan just for you.

Frequently Asked Questions: 

1. Why is balancing carbohydrates important during GLP-1-assisted weight loss?

Balancing carbohydrates is crucial because GLP-1 agonists help regulate blood sugar and appetite. A diet too high in simple carbs can cause blood sugar spikes, leading to weight gain or slowed progress, while low-glycemic carbohydrates can support more consistent energy levels and appetite control. Choosing the right type and amount of carbohydrates helps optimise the effects of GLP-1 therapy for weight loss.

2. How much carbohydrates should women consume while on GLP-1 therapy?

For most women, it is recommended that 45-65% of daily calories come from carbohydrates, depending on individual factors like age, activity level, and weight loss goals. A typical range would be 225 to 325 grams of carbohydrates per day for a 2,000-calorie diet, but this may be adjusted based on personal health needs.

3. Which carbohydrates should I prioritise during GLP-1 therapy?

Women should focus on low-glycemic index (GI) carbohydrates such as:

  • Whole grains (e.g., oats, quinoa, brown rice)
  • Legumes (e.g., lentils, chickpeas)
  • Vegetables (e.g., sweet potatoes, leafy greens) These foods release sugar slowly into the bloodstream, helping to maintain stable blood sugar levels and avoid hunger spikes.

4. What are the risks of consuming too many refined carbohydrates while using GLP-1 agonists?

Over Reliance on refined carbohydrates, such as white bread, sugary snacks, and processed foods, can lead to blood sugar fluctuations, increased hunger, and slower weight loss progress. Refined carbs lack fibre and essential nutrients, which can reduce the effectiveness of GLP-1 agonists in supporting weight loss.

5. Can I eat too few carbohydrates while on GLP-1 therapy?

Yes, drastically cutting carbohydrates can lead to nutrient deficiencies, especially in fibre, which is crucial for digestion and satiety. Women consuming less than 40% of daily calories from carbs may experience fatigue, digestive issues, and poor nutrient intake, hindering overall health and weight loss success.

6. What is the glycemic index (GI), and how does it affect weight loss?

The glycemic index is a measure of how quickly a carbohydrate-containing food raises blood sugar levels. Low-GI foods (e.g., whole grains, legumes) are digested more slowly, leading to better blood sugar control and longer-lasting energy. These foods are ideal for weight loss, as they help prevent insulin spikes and reduce fat storage.

7. Why is fibre important during GLP-1-assisted weight loss?

Fibre slows digestion, enhances feelings of fullness, and supports healthy digestion, all of which are important for weight management. Women should aim for 25-30 grams of fibre per day, which can be achieved by consuming whole grains, fruits, vegetables, and legumes.

8. How can I control my carbohydrate portions without feeling deprived?

One effective way to manage carbohydrate portions is to practise mindful eating, focusing on hunger and fullness cues rather than restricting entire food groups. Using smaller plates, eating slowly, and prioritising fibre-rich, low-GI carbs can also help you feel satisfied without overeating.

9. What common mistakes should I avoid when managing carbohydrates on GLP-1 therapy?

Some common mistakes include:

  • Relying on processed carbs like white bread or sugary snacks, which can hinder weight loss progress.
  • Excessive carb restriction, which may lead to nutrient deficiencies.
  • Ignoring portion control, which can result in overeating even healthy carbohydrates.

10. Can I eat carbohydrates at any time of day while on GLP-1 therapy?

Timing your carbohydrate intake can be beneficial. Many women find that eating complex carbs earlier in the day, when activity levels are higher, helps prevent blood sugar crashes later. Carbohydrates paired with protein or healthy fats can further stabilise blood sugar throughout the day.

11. Should I consult a healthcare professional before changing my carbohydrate intake?

Yes, consulting with a healthcare professional or dietitian is essential to ensure that your carbohydrate intake aligns with your weight loss goals, medical history, and overall health. They can provide personalised advice tailored to your needs during GLP-1 therapy.

References

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