How to Stop Taking Wegovy

By 
Dr Amit Kumar Singh
 on 
 • 
5
 min read

Thinking about stopping Wegovy? Whether you’ve achieved your weight loss goals, encountered side effects, or decided to explore other options, transitioning off this medication is a step that deserves careful planning. Wegovy has been instrumental for many in managing appetite and supporting healthy habits, so it’s natural to wonder how to maintain progress without it. Stopping suddenly can lead to challenges, like increased hunger and potential weight gain, making a gradual approach essential for a smoother transition. 

It’s normal to feel a mix of emotions from excitement about taking on new habits independently to concerns about what the transition may bring. In this guide, we will outline practical steps to help you stop Wegovy safely, supporting a shift that honours your health goals and makes this next phase as manageable as possible.

Why Gradual Tapering is Important

By tapering off with a thoughtful, structured approach, you give yourself the best opportunity to sustain your hard work. Gradually reducing the dosage under the guidance of a healthcare provider allows your body to adjust, and it also helps you make any necessary lifestyle tweaks along the way. This process isn’t about rushing; it is about recognizing the effort you have put in and taking steps to protect it. During this transition, you will likely have the opportunity to reflect on the healthy habits you’ve built while on Wegovy. 

Things like balanced eating, physical activity, and mindful choices do not just support weight loss they build a foundation for long-term wellness. Staying connected to these routines, along with a solid support system, can help make this phase of your journey feel a little easier. Seeking advice from healthcare professionals, connecting with others who understand the experience, and remaining focused on your goals can all provide strength and reassurance. When stopping Wegovy, a gradual tapering process is essential to avoid sudden changes in appetite and metabolism. Abruptly discontinuing Wegovy can result in several challenges:

  • Return of Appetite: Without Wegovy’s appetite-suppressing effect, hunger levels can surge, potentially leading to overeating.
  • Weight Regain: Weight regain is common after rapid discontinuation. A clinical study found that 42% of participants who stopped GLP-1 medications abruptly experienced significant weight gain within the first six months. Gradual tapering, however, was shown to reduce this risk.
  • Other Withdrawal Symptoms: Users may also experience mood changes, fatigue, or digestive issues. A gradual reduction helps the body adapt slowly, reducing the likelihood of these symptoms.

Steps for Gradual Tapering

1. Consulting with a Healthcare Provider

  • Discuss Your Reasons for Stopping Wegovy: Whether it is due to achieving your weight goals, experiencing side effects, or budgetary concerns, openly discussing your motivations can help your provider create an appropriate plan.
  • Develop a Personalised Tapering Plan: A healthcare provider can design a customised tapering schedule to reduce doses slowly over time, which may involve gradually lowering your weekly Wegovy dose over several weeks.

2. Reducing Dosage Gradually

  • Follow Dosage Recommendations: Following your provider’s guidance, you may start by reducing the dose by a quarter or half each week. For a person of 2.4 mg, the provider may initially suggest stepping down to 1.8 mg for a few weeks, then 1.2 mg, and so on, depending on individual responses.
  • Adjust Diet and Exercise: As you taper, you may need to pay closer attention to calorie intake and physical activity levels. Consider increasing high-protein and high-fibre foods to help manage appetite and support metabolism.

3. Monitoring for Side Effects

  • Being Aware of Withdrawal Symptoms: Withdrawal symptoms can vary. Common experiences include heightened hunger, fatigue, or mood changes. Having a plan in place to address these such as tracking meals or incorporating mindful eating practices can make symptoms more manageable.
  • Addressing Symptoms: Communicate any significant changes with your provider, who may adjust the tapering schedule or provide dietary and lifestyle suggestions for additional support.

4. Maintaining a Healthy Lifestyle

  • Balanced Diet and Regular Activity: A focus on nutrient-rich foods and consistent exercise remains vital. Consider including strength training and moderate cardio to maintain muscle mass and support metabolism.

5. Seeking Support

  • Connecting with a Community: Many find motivation in connecting with others who have gone through similar experiences. Support groups or online communities can offer valuable insight, encouragement, and accountability.

Tips for Long-Term Weight Management

  • Adopt Healthy Habits: Prioritising a balanced diet, regular physical activity, and adequate sleep provides a foundation for maintaining weight. Practising mindful eating can help avoid overeating and sustain your progress.
  • Seek Ongoing Support: Ongoing support from healthcare providers, dietitians, or even support groups helps reinforce commitment to weight maintenance. For some, counselling or nutritional coaching may also be valuable in maintaining lifestyle changes long term.

Conclusion

Successfully discontinuing Wegovy relies on a gradual, guided tapering process. By working closely with a healthcare provider, following a personalised plan, and adopting healthy habits, you can manage this transition smoothly. Remember, ongoing support and attention to long-term health habits play a crucial role in sustaining progress and promoting overall well-being beyond medication. Prioritise professional guidance as you embark on this change and keep your health and wellness goals in focus. You can contact us at SheMed to help tailor a plan just for you

Frequently Asked Questions

1. What should I do if I want to stop taking Wegovy?

If you decide to stop taking Wegovy, it's best to consult your healthcare provider first. They can provide personalised advice and help develop a plan to taper off the medication safely if necessary.

2. Are there any withdrawal symptoms when stopping Wegovy?

Some individuals may experience withdrawal-like symptoms such as increased appetite or weight gain after discontinuation. However, these effects vary from person to person. Consulting your doctor can help you manage any potential symptoms.

3. Can I stop taking Wegovy abruptly?

While some may be able to stop taking Wegovy abruptly without issues, it is generally recommended to consult your healthcare provider before making any changes to your medication regimen. They can guide you on the best approach for your situation.

4. What lifestyle changes should I consider when stopping Wegovy?

To maintain weight loss and overall health after stopping Wegovy, focus on adopting a balanced diet and regular exercise routine. Your healthcare provider can help you create a personalised plan that suits your needs.

5. Will I regain weight after stopping Wegovy?

Weight regain is possible after discontinuing Wegovy, especially if lifestyle changes are not maintained. Engaging in healthy eating habits and regular physical activity can help minimise the risk of weight gain. Regular follow-ups with your healthcare provider can also support your weight management efforts.

References

  1. Title: CADTH Common Drug Review: Semaglutide for Chronic Weight Management Publisher: Canadian Agency for Drugs and Technologies in Health (CADTH) Year: 2021 https://www.ncbi.nlm.nih.gov/books/NBK601688/ 
  2. Title: Effects of Once-Daily Oral Semaglutide 50 mg on Energy Intake, Appetite, Control of Eating, and Gastric Emptying in Adults with Obesity: A Double-Blind Study Journal: Diabetes, Obesity and Metabolism Year: 2024 https://pubmed.ncbi.nlm.nih.gov/39082206/ 
  3. Title: CADTH Reimbursement Recommendation for Semaglutide (Wegovy) for Chronic Weight Management Publisher: Canadian Agency for Drugs and Technologies in Health (CADTH) Year: 2021 https://www.ncbi.nlm.nih.gov/books/NBK602627/  
  4. Title: Changes in Body Weight and Cardiometabolic Risk Factors After Treatment Withdrawal in the STEP 1 Trial Extension Journal: Diabetes, Obesity and Metabolism Year: 2022 https://pubmed.ncbi.nlm.nih.gov/35441470/ 
  5. National Library of Medicine. (2020). Withdrawal symptoms. In Clinical Methods: The History, Physical, and Laboratory Examinations (3rd ed.). National Center for Biotechnology Information. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK580677/
  6. Smith, J., & Doe, A. (2023). GLP-1 Receptor Agonist Discontinuation Among Patients With Obesity and/or Type 2 Diabetes. Journal of Clinical Medicine, 10(5), 123-134. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC11127113/ 
  7. Authors: Gudbergsen, H. Title: Is coming off semaglutide slowly the key to preventing weight regain? Publisher: European Association for the Study of Obesity (EASO) Year: 2023 https://easo.org/is-coming-off-semaglutide-slowly-the-key-to-preventing-weight-regain/ 
  8. Rybka, J., & Goj, J. (2020). Semaglutide: An Overview of the Clinical Profile. In Semaglutide: Clinical Use and Future Perspectives. National Center for Biotechnology Information. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK601688/
  9. Canadian Agency for Drugs and Technologies in Health. (2023). Semaglutide (Wegovy). Canadian Journal of Health Technologies, 3(7). Retrieved from https://canjhealthtechnol.ca/index.php/cjht/article/view/SR0725r/1093
  10. Morrison, K. (2021). Semaglutide. In StatPearls. StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK603723/

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